Both resveratrol and grape seed extract are well-known antioxidants. Many people take them as supplements to help with cholesterol, high blood pressure, diabetes, and inflammation. But even more impressive is their anti-cancer power.1 2
Scientists at Penn State conducted a study on rodents with colon cancer tumors. They divided the group into thirds. One-third ate a diet with a combination of grape seed extract and resveratrol. One-third ate a diet supplemented with an anti-inflammatory drug called sulindac. And one-third ate a regular diet.
The rodents on the grape seed and resveratrol diet cut their number of colon cancer tumors in half. The rats in the drug group also saw a decrease in tumors... But they experienced gastrointestinal toxicity—an unpleasant and dangerous side effect. The group on the regular diet saw no significant change.3 4
What’s more, the study found that grape seed extract and resveratrol work better in combination. And despite their power, they aren’t dangerous to healthy cells like the anti-inflammatory drug.5 6
Grape seed extract and resveratrol both come from grapes. But resveratrol is usually harvested from grape skins, while grape seed extract comes from the seed. They have similar antioxidant potency.
But they each have their strengths... For instance, grape seed extract is the better option for treating diabetes. Resveratrol is better for heart disease.7 This study shows it’s best to supplement with both—especially when it comes to cancer prevention.
References: 1 http://www.webmd.com/heart-disease/resveratrol-supplements 2 http://www.umm.edu/health/medical/altmed/herb/grape-seed 3 https://www.pakistantoday.com.pk/2017/06/30/grape-extracts-may-protect-against-colon-cancer/ 4 https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1254-2 5 https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1254-2 6 https://www.pakistantoday.com.pk/2017/06/30/grape-extracts-may-protect-against-colon-cancer/ 7 http://www.livestrong.com/article/266890-what-is-the-difference-between-resveratrol-grape-seed-extract/ 8 http://www.livestrong.com/article/266890-what-is-the-difference-between-resveratrol-grape-seed-extract/